Malaria Control by Anti-Mosquito Measures

Malaria Control by Anti-Mosquito Measures

The mosquito-malaria theory.

Mosquito-Malaria Hypothesis

over our food or drowns itself in our drink, the gnat that buries its lancet in our veins, the bed-bug that attacks the uncleanly during the slumbers of the night, the wasp and the bee that thrust us with their stings?are all transporters, injectors or introducers of germ life. "My reasons for affirming this are briefly comprised in the statement that I have never known a person suffer from mal...

Disrupting Mosquito Reproduction and Parasite Development for Malaria Control

The control of mosquito populations with insecticide treated bed nets and indoor residual sprays remains the cornerstone of malaria reduction and elimination programs. In light of widespread insecticide resistance in mosquitoes, however, alternative strategies for reducing transmission by the mosquito vector are urgently needed, including the identification of safe compounds that affect vectori...

Novel Acetylcholinesterase Target Site for Malaria Mosquito Control

Current anticholinesterase pesticides were developed during World War II and are toxic to mammals because they target a catalytic serine residue of acetylcholinesterases (AChEs) in insects and in mammals. A sequence analysis of AChEs from 73 species and a three-dimensional model of a malaria-carrying mosquito (Anopheles gambiae) AChE (AgAChE) reported here show that C286 and R339 of AgAChE are ...